- 05-11-2018Introduction Monogenic mutations in genes part of the leptin-melanocortin pathway are proven to cause obesity, with the highest reported prevalence…
- 05-11-2018IntroductionSevere protein malnutrition, with a serum albumin < 25 g/L, is one of the complications that may develop after bariatric…
- 04-11-2018IntroductionAdolescents spend much time using blue-light emitting screen devices such as smartphones, tablets and computers. Blue light affects the central…
- 02-11-2018Sex differences on brown adipose tissue (BAT) function and abundance have been studied in many species: BAT of female mice…
- 01-11-2018BACKGROUND: Congenital hypothyroidism (CH) comprises disorders of either the thyroid gland (CH-T) or the regulatory system stimulating the thyroid gland…
- 01-11-2018BackgroundApproximately 60% to 80% of patients with congenital central hypothyroidism (CH-C) have multiple pituitary hormone deficiencies (MPHDs), making CH-C a…
- 01-11-2018IntroductionThe transcriptional activation of thyroid hormone receptors (TRs) involves the recruitment of nuclear coregulatory proteins. There is evidence for tissue-specific…
- 31-10-2018In craniopharyngioma patients, an important clinical feature is an adverse metabolic profile due to hypothalamic damage and pituitary deficiencies. Previously,…
- 31-10-2018Background: Pheochromocytomas or paragangliomas (PPGLs) caused by mutations in the β-subunit of the succinate dehydrogenase (SDHB) have the highest metastatic…
- 31-10-2018Fibrous dysplasia (FD) is a congenital, non-hereditary bone disease with a clinical presentation ranging from mild monostotic disease to the…
