- 19-11-2023Background Patients with non-functioning pituitary macroadenoma (NFMA) currently have no established medical treatment options. Somatostatin analogues may decrease tumour size,…
- 16-11-2023Introduction: Romosozumab, a monoclonal anti-sclerostin antibody, is an osteoporosis drug available in the Netherlands since 2021 indicated for patients with…
- 16-11-2023Background: Chronic nonbacterial osteomyelitis (CNO) is a rare disease spectrum, which lacks biomarkers for disease activity. Sodium fluoride positron emission…
- 15-11-2023Background: Fibrodysplasia Ossificans Progressiva (FOP) is an invalidating disorder marked by severe heterotopic ossifications (HO), causing diffuse ankylosis and early…
- 15-11-2023Background:Pathogenic variants in the LRP5, PLS3, or WNT1 genes can significantly affect bone mineral density, causing monogenic osteoporosis. Much remains to be discovered…
- 15-11-2023ABSTRACTIntroduction: The combination of disease manifestations, a familial burden and the rare genetic etiology serve a unique impact on Quality…
- 15-11-2023IntroductionA comprehensive and uniform collection of data on head and neck paragangliomas (HNPGLs) is lacking due to its rarity and…
- 15-11-2023Objective: Gestational thyroid dysfunction and gestational diabetes mellitus (GDM) are common complications during pregnancy and often co-occur. Since thyroid hormones…
- 15-11-2023Objectives: Thyroid function has long been associated with body composition in the general population. Little is known regarding the association…
- 14-11-2023Congenital adrenal hyperplasia (CAH) is an inherited adrenal steroid synthesis disorder, included in the Dutch Newborn Screening (NBS) since 2002.…