- 05-09-2019Background Glucocorticoids regulate pivotal processes such as metabolism and inflammation via the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR).…
- 23-08-2019Context: Hormones of the hypothalamic-pituitary-target gland axes are mostly investigated separately, while the interplay between hormones might be as important…
- 23-08-2019Context: Hormones of the hypothalamic-pituitary-target gland axes are mostly investigated separately, while the interplay between hormones might be as important…
- 15-08-2019Metastatic castration-resistant prostate cancer (CRPC) remains a clinical challenge despite antitumoral therapies such as taxane chemotherapeutics, enzalutamide, and abiraterone acetate.…
- 15-08-2019IntroductionGhrelin, a 28-amino acid gut hormone, occurs in acylated (AG) and unacylated (UAG) variants. AG, acting via the growth hormone…
- 14-08-2019Polycystic ovary syndrome (PCOS), the most common endocrine disorder in women, is diagnosed based on three criteria, including a polycystic…
- 08-08-2019Background: The ENSAT-HT project aims to discover biomarkers for forms of adrenal hypertension (AHT) based on a multi-omics approach, including…
- 01-08-2019Testicular Adrenal Rest Tumors (TART) are a common complication in patients with Congenital Adrenal Hyperplasia (CAH), leading to irreversible damage…
- 23-11-201825-hydroxyvitamin D is mainly susceptible to hydroxylation on two positions. Hydroxylation on the 1-position by CYP27B1 yields the hormonally active…
- 14-11-2018Background: Type 2 Diabetes Mellitus (T2DM) is associated with an increased risk for cardiovascular disease. Postprandial hyperlipemia as characteristic for…
