- 07-10-2021Background: Patients with diabetes mellitus (DM) are prone to develop vascular calcification and have a substantially increased cardiovascular risk. Since patients with DM display higher expression of phosphate transporters in vascular smooth muscle cells, these patients…
- 07-10-2021AbstractIntroduction: Respiratory failure is a major cause of death in patients with Osteogenesis Imperfecta. Moreover, respiratory symptoms seem to have a…
- 04-10-2021Objective: Subclinical thyroid disease and even variation in normal range thyroid function have been associated with various adverse health outcomes. While…
- 04-10-2021IntroductionHypothalamic obesity (HO) in children may have severe consequences. Lifestyle interventions are often insufficient and no effective drug treatment is…
- 17-09-2021Creatine availability in adipose tissue has been shown to have profound effects on thermogenesis and energy balance in mice. However,…
- 17-09-2021Background and objectiveThe importance of the brain as a regulator in glucose homeostasis is emerging. Central dopaminergic activity follows a…
- 17-09-2021Background: Obesity (BMI ≥ 30 kg/m2) is a chronic disease which is associated with disturbances in metabolism and eating behaviour…
- 17-09-2021Background: Obesity (BMI ≥ 30 kg/m2) is a chronic disease which is associated with disturbances in metabolism and eating behaviour…
- 17-09-2021Context: Little is known about the effects of puberty suppression (PS) and hormone therapy (HT) on growth and adult height…
- 17-09-2021IntroductionMelanocortin-4 receptor (MC4R) is a G-protein coupled receptor expressed in regions of the hypothalamus that regulate appetite and energy expenditure.…