- 30-11-2022Background/purpose: Chronic non-bacterial osteomyelitis (CNO) is a rare bone disease spectrum with pediatric and adult presentations. Pediatric CNO is hypothesized…
- 30-11-2022New treatment options are needed to prolong the life of patients with end-stage prostate cancer (PCa) that is resistant to…
- 30-11-2022Introduction: Blood glucose regulation of women with type 1 and type 2 diabetes changes around menopause, which may be partly…
- 30-11-2022Differentiated thyroid carcinoma (DTC)-survivors have an increased risk for cardiovascular mortality yet, the pathophysiological mechanism remains unknown. During early treatment…
- 30-11-2022Background The role of insulin growth factor 1 (IGF-1) in the etiology of cancer is an ongoing subject of debate.…
- 30-11-2022Huntington’s Disease (HD) is a genetic neurodegenerative disease caused by a mutation in the huntingtin gene. Mutant huntingtin (mHtt) leads…
- 30-11-2022Huntington’s Disease (HD) is a genetic neurodegenerative disease caused by a mutation in the huntingtin gene. Mutant huntingtin (mHtt) leads…
- 30-11-2022In the brain, mineralocorticoid (MR) and glucocorticoid receptors (GR) act as transcription factors to mediate effects of glucocorticoid (GC) hormones…
- 30-11-2022Next Generation Risk Assessment (NGRA) can use the Dietary Comparator Ratio (DCR) to evaluate the safety of a defined exposure…
- 30-11-2022CORT118335 (miricorilant) is a GR ligand that acts as a selective modulator of GR activity by inducing a combination of…
